RAF Typhoon fighter aircraft have operated alongside French aircraft in a coordinated attack targeting an hidden munitions depot in Syria employed by the IS group, according to the UK Ministry of Defence.
The facility, located using surveillance, was assessed as storing arms and explosives, the statement said, and was positioned in hills just to the north of the ancient city of Palmyra in Syria's central region.
"Our aircraft employed precision-guided Paveway IV munitions to strike a series of approach shafts providing entry to the facility... preliminary assessments indicate the strike was effective," officials stated.
There was no indication of any civilian casualties in the strike conducted Saturday night and every plane involved made a safe return, the ministry further stated.
The British jets were assisted by a Voyager tanker plane.
Daesh - also known as Daesh - enforced militant control over significant areas in Iraq and Syria prior to its 2019 collapse.
"This strike shows our UK leadership, and resolve to stand shoulder to shoulder with our partners, to stamp out any revival of the terrorist group and their harmful and extremist ideologies in the area," UK Defence Secretary the minister said.
RAF aircraft have performed patrols over Syrian airspace to "prevent any efforts to regroup" of the group after its routing at the Baghuz confrontation in the year 2019, the ministry said.
"I want to thank every member of British forces involved in this strike for their expertise and their bravery," the Defence Secretary added. "Including them were thousands of UK service members deployed over Christmas and New Year. This action, to remove militants who pose a risk to our way of life, demonstrates how British military are prepared to act, all year round, ensuring Britain's security domestically and strong abroad."
During December, the US military executed what it called a "large-scale strike" targeting Daesh sites in the country, subsequent to an assault claimed the lives of two US troops and a civilian linguist in Palmyra.
The United Nations estimates Islamic State still boasts an estimated 5,000 to 7,000 combatants in both countries.